Florence, SC Airport
- URL: Florence, SC (FLO)
- Time zone: GMT -5
- Service telephone: +1 843 669-5001
- Address: Florence Regional Airport, 2100 Terminal Drive, Florence, SC 29506, USA
- Operating company: City & County of Florence
- Flight distribution on the days of the week: Monday (14.04%), Tuesday (14.04%), Wednesday (13.36%), Thursday (14.04%), Friday (14.38%), Saturday (14.73%), Sunday (15.41%)
- Alternative spelling: Florence-SC, Флоренс (Южная Каролина), フィレンツェ (サウスカロライナ州), 佛罗伦萨 (南卡罗来纳州)